Epidermolysis bullosa aquista (Eba) is a rare chronic auto immune disease that causes skin blisters. This blister may appear to minor injury, rubbing or even from heat exposure. Eba is a subepidermal disease with an incidence of 0.1 new cases per million per year. Eba is characterized by autoimmunity to type VII collagen located at dermis and epidermis junction that alters the normal functioning of anchoring fibrils. Eba has no permanent cure and treatment mainly focus on caring for blisters and prevent new ones. Some treatment success has been with corticosteroids, dapsone, plasmaphoresis, photopheresis.
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